Am I crazy to try again? On the way to IVF#5 at 43

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  • Started by lagaluga1987 ago.
  • Latest reply from lagaluga1987.
  1. Baby - That is so exciting to be starting stims. Keep us posted on your first sono. No news here, I'm still researching clinics for my last and final IVF. I don't plan to cycle until September / October.

  2. butterflies, thanks again for your wishes.

    sadkiab, had my US today. Dr didn't want to give me much info because he says its still very early, that we will know more definitevely on Saturday's check. After 4 days of stims, follies are stil small he said, not sure if they would mature, there were 8 or 9. I'm looking forward to hearing my E2 level later. When is your CCRM consult?

    Eros, so glad you joined us! You will be riding the wagon again soon hopefully to the pot of gold at the end of the rainbow!
    I must say that something inside me drives me feverishly to NOT GIVE UP, I can't, not yet.

  3. Hi Ladies...

    I am about to start IVF nbr 3 ... Yeah ,,,,

    I have decided that it must be like Childbirth.... you forget all the pain it causes and just get on to have one more ! Not that I have a child ... I just Imagine!

    Miss Sunny... Can you tell us your exact protocol and the meds you are taking.

    Hello lagaluga1987 ... Thanks for inviting me over to this forum.. I'm looking forward to seeing good advice and results here. I admire your get on the wagon again attitude - I have to do it too... I just need to feel like I gave it all my BEST shot !

    Pregger wishes to all.

  4. Hi Ladies, I haven't abandoned you. I just want to answer every one of your questions and I've been so tired this week that I haven't had the energy to do it. I promise I'll get back soon and do that.

  5. lagaluga1987 - 8-9 follies sounds really good. It sounds like your RE doesn't want to give you too much info and stress you right now. All you need is a good quality egg from that. Be sure to avoid any stress, especially around ovulation - I know easier said than done. Where are you cycling?

    Miss sunny - no worries about feeling too tired right now. Just take good care of yourself. It's just great to hear from you and be inspired by your success.

    Eros - welcome, I will be starting my IVF #3, too. Like you, I just want to feel I've given this my best shot.

    Matty, Manthos, ecocity, phlomis, butterflies, how is everyone doing?

    Okay, I need to rant a little...So, I just went on a consult with a new RE today. It was pathetic. Instead, he was in with another patient for almost an hour before I got to see him. In the meantime, they tried to fill time by taking my weight, bloodpressure, and having the nurse talk with me about the DE option. I told her that I was not there to talk about that yet. Once I met with the RE, he hadn't had but a couple of minutes to look over my files. He recommended the same protocol (injections/Antagon) as what was used for IVF #1. He didn't offer any sort of twist on the old, and said he didn't use the EPP protocol because he hadn't seen that it was any more successful than the FSH injections/Antagon protocol. What? I mentioned that I had seen a lot of AMAs having success with EPP/Saizen and dexamethasone, but he was not at all knowledgeable or interested in trying that. I've decided that if the RE isn't interested in trying something progressive, then I'm not going to waste my time.

  6. sadkiab... Will you turn on your PM, so I can send you a PM? Thanks.

  7. miss sunny, rest up and take good care of yourself, we'll be here when you are up to it

    sadkiab, I don't think you will be cycling w/that RE next, I wouldn't be too happy about the experience. I'm sorry that you went through that, ESPECIALLY the Donor speech. I have made it very CLEAR to any RE that I have gone to NOT to even attempt the conversation, I won't have it.
    Don't stay upset, it's not worth it, now you know that this is not the doctor that you want to leave your fate up to. Sounds like a moron, when you are looking for cutting edge, right? Forget about it and go to the next. How many more places are you willing to consult at? You need to feel very very comfortable w/the clinic and the RE, this is way to important, if you aren't feeling confident w/them, your battle w/be that much harder, and we all know it's hard enough already, right?

    How are the rest of you ladies doing?

    AFM, my E2 was only 222 yesterday after 4 days of stims, I thought it would be higher than that, but hopefully tomorrow w/look better. I'm guessing my ER will be 7/30, I'm hoping to hold off so that I can attend my buddies bridal shower on Saturday, 8/1, but I won't be able to go if I have ER on 7/29, because then it will be transfer day 3, and I've NEVER did a 5 day in the past.
    Hope everyone is having a great day.

  8. skanavi - I'm not sure, but I think I figured out how to turn on PM. I sent you a PM Friday am, but then completely lost internet access and it was up and down until late last night. Please feel free to PM me when you are on.

    lagaluga1987 - Is your RE concerned about your E2 not rising enough? I thought it was a bad thing if it rises too fast. I checked my E2s from my 2 IVFs . Last year (age 42.4), on IVF #1 E2 on day 5 (of stims) was 337, day 7 it was 837, and by day 9 it was 1709. I ended up with 8 eggs, 3 put back in. Only 3 of those were 6-8 cells on day 3. For IVF #2 (age 42.10), it was 383 on day 6 and to 1080 on day 8. I ended up with similar results: 11 eggs, 4 put back in but only 2 were 7-8 cells. I was told by one RE that it was bad for E2 to get too high (fries egg), but I think he was talking about E2s of something like 6000.

    AMF, My consult with Dr. Sch at CCRM is Aug. 13. I have another consult with another local RE next week, but part of me wants to just cancel that one, because I really have decided in my mind that I want to go to CCRM. I look at the SARTs reports and almost none of the local docs have any success with 43-44 year olds. Also, there is a lot of turnover at the best labs locally - doctor's are taking those experienced embryologists and starting their own labs. All of that shuffling concerns me. I'm just trying to get figure out how to tell DH that I want to spend a lot more $$ and experience great inconvenience in order to give this my last best shot. After that, I will be ready to go on to DE.

  9. E2 is only 540 after 6 days of stims w/4 follicles maturing and some small ones that may or may not do anything. I'm being increased to 3 menopur and starting Ganilerex on Monday. I really hope that the little guys start to catch up and I get more to work with. I can obsess over it all or just sit back and see what happens and try not to drive myself crazy.

    Hope everyone is having a good weekend. Gnight

  10. No, not crazy. The REs told me I had hardly a chance in the world, and they were right, as far as the statistics go. I told myself that I would give up at age 44 (that's also the age cut-off for the clinic I was going to at the time). But it turns out my IVF journey was just starting. I switched clinics again. And I did 8 additional IVF cycles back-to-back until getting a BFP age 44.8 on a fresh transfer. Delivered a healthy boy age 45.

    At our age, diet, protocol etc doesn't really matter so much as finding the right egg, and I believed that my body was trying to produce that egg, every month. So for me the \"plugging away at it\" attitude was key. I could have afforded to do one or two cycles at a top clinic, but since the issue was egg quality, I chose to cycle at reasonable, local places with less drugs so I could keep going.

    But you may not want to hear that I ended up doing 13 IVF cycles at four clinics. Oh well, everyone has their limits. Aside from sheer persistence, I think that I got lucky. Very lucky.

  11. ulke - Thank you for taking the time for sharing your story. These stories keep me going. I am 42, going on my 5th cycle and plan to keep going.

    Can I ask where you cycled locally that didn't give you a hard time cycling at 44? That is what I am afraid I will have a problem with. I am with Cornell now, but paying a lot out of pocket and may have to go back to local clinics to use my insurance at some point. Thanks.

    Congratulations!

  12. sadkiab, I'm glad that you have decided to go to CCRM, their SART statistics are great for us older girls, I think the lab there is the best, and having experienced them first hand for one cycle, I was very impressed. If you would like more info, I would be very happy to PM w/you. Even though I got another BFN there, my cycle was better.

    ulke, thank you so much for your story, I am so thrilled to hear it. Your presistance and strength certainly paid off. How did you cope w/the numerous BFNs? Did you join a support group or something? I have found it helpful to talk to someone (therapy) to deal w/the battle and depression of defeat. It has certainly made me deal better and I am really trying to stay calm this time. I have decided to try to keep my emotions low and not have any great expectations that will destroy me, but at the same time, obviously hold on to hope and keep plugging away, I just don't know how much longer and I can fight, hopefully I won't have to for much longer.
    Your story is so inspirational and much appreciated. How old is your miracle baby boy now?

    Anna_Maria, do you have any coverage at least for medications?
    Out of pocket certainly makes the journey all the more difficult. Hopefully #5 will be the magic number for both of us.

    My update:
    E2 has been rising nicely, yay!!!! It went up to 1253 after 7 days of stims. Dr. says at least 5 mature follies look good, the largest today was 21 then a 20. Of the smaller ones that he had ruled out yesterday, the largest was 9.5 and it shot up to 13 today, there's a chance that I might get more than 5 mature, I can only hope.
    I'm looking forward to hearing what today's E2 level was for today after 8 days of stims, and what time I trigger tonight, hopefully early. So ER is Thursday, 7/30/09 and ET will be Sunday, 8/2, which means I get to go to my gf's bridal shower Saturday. I'm so happy not to miss it.

  13. Baby - I have full coverage for everything, but with Cornell being out of network, it still costs me $8,000 to $10,000 out of pocket. I am not a big fan of the few in network local facilities....

    Good luck with your cycle.

  14. Ladies,
    I am in awe of all of your wonderful attitudes. I hope you don't mind if I join. I am 42, and have a 4 year old from my first cycle at 37 with IVF/PGD. I have a chromosonal issue and had had 3 natural m/c before turning to IVF. After she was born on our first try, we were overconfident and waited a year (39) before trying for a number 2. We have done 8 cycles in attempt for number 2, all BFN.

    Twice I have been scheduled for a donor cycle and backed out at the last minute. I wish I could just make that the option for me but I haven't been able to give up on my own yet. The last donor attempt, I got physically sick, and stricken with anxiety. I canceled and converted the cycle to one of my own, which just ended really badly. 3 eggs retrieved, nothing to transfer.

    This was very odd for me as I have a low fsh, 6.5 and have always had tons of eggs. 16 on my last cycle at 41.9. I think my RE really screwed this cycle up and I actually told him so when I spoke with him this morning. I have had only 2 bad cycles and they were both ANTAGON cycles. When he prescribed it this time, I told him I didn't react well to it and he insisted. Again, a terrible cycle. My first with nothing to transfer.

    I wish I could just move on to donor, but somehow I can't. So I'm here with all of you, wishing, hoping, praying and forging foreward.

    agostino

  15. lagaluga1987 - Yay, I'm knew your E2 levels would go up! Keep us posted on how things go on Thursday.

    ulke - your story is a good example that at our age, we have to do multiple cycles to be successful. When you say less IVF drugs, how much did you use for your cycles?

    agostino, welcome. I'm so sorry about all the BFNs. I know exactly what you mean when you mention being overconfidant after success from your first attempt. I also have a 4yr old from 1st IUI when I was 38. We waited 22 months. I'm hoping to do one last cycle with my own eggs before going to DE. And once I make that decision to go to DE, I will be so relieved. But, I'm not there yet. I need closure. Regarding your RE messing up your cycle, are you planning to stay with him or go to someone else? I've heard that if you see someone a couple of cycles, and if they are not tweaking your stims, or reevaluating, then it's a good idea to consult with someone else.

  16. Thanks for the welcome.
    I think I am done with cycling. Not because I don't think it is possible, but it is such a negative experience. I wish I had done this last one at CCRM, but it was just very expensive and also I didn't have it in me to do all the initial testing all over again.

    I am going to have a conference with the head of the Fertility Center I go to. They are very highly regarded and it is just this one doctor in the group that is cavalier with people's cycles, I believe. I am going to complain to the head doc that I had told him in advance that I had a bad reaction to Ganirelex/Antagon, and he pushed me (for the second time, unsuccessfully) when all my micro dose lupron cycles have yielded huge amounts of eggs.

    He was happy to leave me with a fertility death sentence of \"crappy old eggs\" when just 2 months ago I did an IUI on low dose meds and got 8 big follies.
    Idiot. If the head doc offers me a free cycle I really don't even want it. I am really trying to move on to DE or adoption. I think both have huge advantages and huge disadvantages and I just don't know which way to go.

    Since my daughter will be 5 by the time either DE or adoption come through, part of me thinks it would be better to adopt a baby slightly older, maybe a year or 16 months so that they will be closer in age since that's always what we wanted.

    ulke, I love your story, you are like the Dara Torres of Fertility.

    agostino

  17. No, not crazy. The REs told me I had hardly a chance in the world, and they were right, as far as the statistics go. I told myself that I would give up at age 44 (that's also the age cut-off for the clinic I was going to at the time). But it turns out my IVF journey was just starting. I switched clinics again. And I did 8 additional IVF cycles back-to-back until getting a BFP age 44.8 on a fresh transfer. Delivered a healthy boy age 45. At our age, diet, protocol etc doesn't really matter so much as finding the right egg, and I believed that my body was trying to produce that egg, every month. So for me the \"plugging away at it\" attitude was key. I could have afforded to do one or two cycles at a top clinic, but since the issue was egg quality, I chose to cycle at reasonable, local places with less drugs so I could keep going. But you may not want to hear that I ended up doing 13 IVF cycles at four clinics. Oh well, everyone has their limits. Aside from sheer persistence, I think that I got lucky. Very lucky.

    Very Inspirational story, thank you for sharing
    At 41.9 on my 5th IVF cycle, you have given me hope

  18. Hi ladies, can I join in?
    First, I can't believe I will be 42 in a month. Where did the time go??
    Great career, great husband (married at 37) but babyless.

    After 7 iui's - 1 success but 8 wk m/c
    2 IVF's in NYC - BFN great eggs response (1 ins pd for 1 out of pocket) 15k
    2 IVF's in Israel - BFN great egg response 1 and dwindled June (ofp- 3500ea)

    I think we are ready to move to DE. Thought long and hard about it the last 6 months. Accepting the baby will be hubby dna and not mine was me rationalizing that I was always ok with adopting a child and he isn't so I think we have a compromise in DE.

    I keep saying I'm only 42 and can keep trying for anothe 2-3 times, but cannot afford it in NYC, I would have to go abroad. Craziness. But more importantly, I feel differently about my body now, really, does anyone else feel a toll on themselves physically? I feel my hormones have changed or just that I don't feel as healthy as a horse like I did at 38. Anyways, can you send me your concerns on DE. I want to make sure I am covering all bases here. Issues, etc.
    DE here in NYC has referred me to CT which came to a cost of $30k.
    I'm investigating all the UK women running to E.Europe with success at a cost of $7k.
    Thoughts to consider please?? I'm about 90% but still have hesitation and not sure why.

    Thanks.

  19. Hello ladies,
    I\'m on my way to ER! I will post to everyone when I get back, Wish me luck!!!
    E2 was 1629 yesterday, up from 1441 the day before. Hope this is a good sign. I am so nervous, I've kept cool until now

  20. Hello everyone! I am new and have come to this forum for the much praised support you provide for one another. Iam also new to chat rooms, so forgive me if this is inthe wrong place. My primary concern is that my friend and donar, a 30 year old, missed an Estrogen dose about 10 days before we did the egg retrival, which ended up being a week later than planned. The first two transfers didn't work, one fresh , one frozen, and now my doc is saying maybe the embros are comprimised. Has anyone had success after a mistake like this, or heard of success in this situation? I am trying so hard, like everyone trying to concieve here, to stay Myrto and believe the miricle can still happen for me too. Thanks to all, Katie G. Aka daskalos

  21. ulke - I just tried to send you a private message and your mailbox is full. In case you read this....

  22. Baby - Good luck to you!!!!

  23. Update: they got 7 eggs, I am feeling pretty bad, ovaries very sore, and when I take a deep full breath, pain on my right side. I'm going to lie down for the afternoon and try to get back to the computer to catch up and respond to everyone.

  24. Baby ~ Great news, lucky #7 and all. Take it easy and rest - I look forward to hearing your fert report tomorrow. Even though I had to quit cycling I still love cycle details...

    CD 1 for me today. That officially ends my m/c and d&c cycle. Now, I try that old fashioned way. I \"hear\" it works for some people ... lol, one good egg meet one good sperm...

    ~Matty

  25. Ehukai: I'm sorry you're having to go through this. It's so hard. I'm not sure I understand, but it seems like missing one estrogen dose would not greatly affect embryo quality. Success rate and egg quality can be quite variable for egg donors, with rates up to 75% at some of the better clinics. Unfortunately, egg donor cycles can be unsuccessful, especially when they are \"unproven\". You may also want to have an immunity panel done to make sure that your body is not rejecting the embryo.

    Hello everyone! I am new and have come to this forum for the much praised support you provide for one another. Iam also new to chat rooms, so forgive me if this is inthe wrong place. My primary concern is that my friend and donar, a 30 year old, missed an Estrogen dose about 10 days before we did the egg retrival, .....

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